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1569. A Translational Model to Assess the Impact of Polymyxin B Dose Fractionation on Kidney Injury
BACKGROUND: Progression of antimicrobial resistance has revived Polymyxin B (PB) use in clinical practice. Dose-dependent acute kidney injury (AKI) limits its clinical use. It is unclear whether dose fractionation of total daily dose can lessen kidney injury. We assessed the role of PB fractionation...
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| Udgivet i: | Open Forum Infect Dis |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6809707/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.1433 |
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