852. The Cefazolin Inoculum Effect and Methicillin-Susceptible Staphylococcus aureus Osteoarticular Infections in Children: Does It Matter?

BACKGROUND: Select methicillin-susceptible Staphylococcus aureus (MSSA) strains may produce β-lactamases with an affinity for first-generation cephalosporins (1GC). In the setting of a high inoculum, these β-lactamases may promote clinically meaningful cleavage of 1GCs, potentially resulting in anti...

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Udgivet i:Open Forum Infect Dis
Main Authors: McNeil, Jonathan C, Sommer, Lauren, Boyle, Mary G, G. Hogan, Patrick, G. Vallejo, Jesus, Hulten, Kristina G, Kaplan, Sheldon L, Fritz, Stephanie
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809393/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz359.037
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