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1726. Candida albicans Virulence Genes Induced During Intra-abdominal Candidiasis (IAC) in the Absence of Antifungal Exposure Mediate Echinocandin Resistance
BACKGROUND: We developed and validated a mouse model of C. albicans IAC that mimics peritonitis and abscesses (IAA) in humans, and that is amenable to temporal–spatial transcriptional profiling and virulence studies. METHODS: We measured C. albicans SC5314 gene expression by RNA-Seq (RiboPure extrac...
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| Publicado no: | Open Forum Infect Dis |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6809290/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.1589 |
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