975. Roles of Type I and III Interferon in Severe Pathogenesis of Human Metapneumovirus

BACKGROUND: Human metapneumovirus (HMPV) is a leading cause of respiratory tract infection in children and adults. However, mechanisms of pathogenesis are not fully understood. METHODS: We tested HMPV clinical and laboratory isolates in an established C57BL/6 mouse model and measured weight loss, ai...

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Veröffentlicht in:Open Forum Infect Dis
Hauptverfasser: Williams, John V, Zhang, Yu, Xu, Jiuyang, Miranda-Katz, Margot, Rich, Helen, Manni, Michelle, Tollefson, Sharon, Sarkar, Saumendra, Alcorn, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809077/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz359.077
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