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78. Oral Norovirus Vaccination in Humans Induces Plasmablast B-Cell Expansion and Follicular T-Cell Activation Comparable to Natural Infection

BACKGROUND: Norovirus (NoV) is a common cause of acute gastroenteritis, but no vaccines are currently licensed. Vaxart is developing an oral tableted NoV vaccine that induces both systemic and mucosal immune responses. METHODS: Two separate clinical studies were conducted to evaluate the safety and...

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Pubblicato in:Open Forum Infect Dis
Autori principali: Mateo, Roberto, Lin, Karen, Kolhatkar, Nikita, Taylor, David, Garg, Shaily, Tucker, Sean
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808692/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz359.002
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