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Safety and immunogenicity of an oral tablet norovirus vaccine, a phase I randomized, placebo-controlled trial

BACKGROUND. Noroviruses are the leading cause of epidemic acute gastroenteritis and foodborne diarrheal disease in humans. However, there are no approved vaccines for noroviruses. Potential correlates of protection identified through human challenge studies include mucosal IgA, memory B cells, and s...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Kim, Leesun, Liebowitz, David, Lin, Karen, Kasparek, Kassandra, Pasetti, Marcela F., Garg, Shaily J., Gottlieb, Keith, Trager, George, Tucker, Sean N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124525/
https://ncbi.nlm.nih.gov/pubmed/29997294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121077
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