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Safety and immunogenicity of an oral tablet norovirus vaccine, a phase I randomized, placebo-controlled trial

BACKGROUND. Noroviruses are the leading cause of epidemic acute gastroenteritis and foodborne diarrheal disease in humans. However, there are no approved vaccines for noroviruses. Potential correlates of protection identified through human challenge studies include mucosal IgA, memory B cells, and s...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Kim, Leesun, Liebowitz, David, Lin, Karen, Kasparek, Kassandra, Pasetti, Marcela F., Garg, Shaily J., Gottlieb, Keith, Trager, George, Tucker, Sean N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124525/
https://ncbi.nlm.nih.gov/pubmed/29997294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121077
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