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Top-Down ETD-MS Provides Unreliable Quantitation of Methionine Oxidation

Methionine oxidation plays a critical role in many processes of biologic and biomedical importance, including cellular redox responses and stability of protein pharmaceuticals. Bottom-up methods for analysis of methionine oxidation can suffer from incomplete sequence coverage, as well as an inabilit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biomol Tech
Hauptverfasser: Tadi, Surendar, Sharp, Joshua S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association of Biomolecular Resource Facilities 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808186/
https://ncbi.nlm.nih.gov/pubmed/31662705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7171/jbt.19-3004-002
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