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Quantitative detection of platelet GPIIb‐IIIa receptor antagonist activity using a flow cytometric method

Platelet‐membrane surface receptors are important targets for pharmacologic intervention in cardiovascular disease. Among these, glycoprotein (GP) IIb‐IIIa is dominant and integrally involved in platelet aggregation and thrombus formation. When activated, GPIIb‐IIIa binds soluble fibrinogen (Fb) in...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Green, Lisa J., Marder, Philip, Um, Suzane L., Jakubowski, Joseph A., Lawrence, Jeffry B.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808160/
https://ncbi.nlm.nih.gov/pubmed/9671169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/(SICI)1098-2825(1998)12:4<191::AID-JCLA1>3.0.CO;2-B
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