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Elevating local concentrations of GPIIb–IIIa antagonists counteracts platelet thrombus stability

Glycoprotein IIb–IIIa (GPIIb–IIIa) antagonists have the capacity to destabilize coronary thrombi and restore vessel patency. Antagonist concentration and residence time, which can be increased by local intracoronary (LIC) administration, and thrombus age may be key factors that influence thrombus st...

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Autores principales: Speich, Henry E., Furman, Ronit R., Lands, Lindsey T., Moodie, Geoffrey D., Jennings, Lisa K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682094/
https://ncbi.nlm.nih.gov/pubmed/23073747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11239-012-0814-7
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