A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors

Trypanosoma cruzi carbonic anhydrase (TcCA) has recently emerged as an interesting target for the design of new compounds to treat Chagas disease. In this study we report the results of a structure-based virtual screening campaign to identify novel and selective TcCA inhibitors. The combination of p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Enzyme Inhib Med Chem
Egile Nagusiak: Llanos, Manuel A., Sbaraglini, María L., Villalba, María L., Ruiz, María D., Carrillo, Carolina, Alba Soto, Catalina, Talevi, Alan, Angeli, Andrea, Parkkila, Seppo, Supuran, Claudiu T., Gavernet, Luciana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2019
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807911/
https://ncbi.nlm.nih.gov/pubmed/31619095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1677638
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