A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors

Trypanosoma cruzi carbonic anhydrase (TcCA) has recently emerged as an interesting target for the design of new compounds to treat Chagas disease. In this study we report the results of a structure-based virtual screening campaign to identify novel and selective TcCA inhibitors. The combination of p...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Llanos, Manuel A., Sbaraglini, María L., Villalba, María L., Ruiz, María D., Carrillo, Carolina, Alba Soto, Catalina, Talevi, Alan, Angeli, Andrea, Parkkila, Seppo, Supuran, Claudiu T., Gavernet, Luciana
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807911/
https://ncbi.nlm.nih.gov/pubmed/31619095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1677638
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