Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles

A series of 6-substituted ureido- and thioureido-benzoxaboroles were investigated as inhibitors of carbonic anhydrases from Trypanosoma cruzi (TcCA), and Leishmania donovani chagasi (LdcCA). Both enzymes were inhibited by benzoxaboroles in the micromolar range. Preferential inhibitory potency agains...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Nocentini, Alessio, Cadoni, Roberta, Dumy, Pascal, Supuran, Claudiu T., Winum, Jean-Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009872/
https://ncbi.nlm.nih.gov/pubmed/29278948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1414808
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