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Reticulocyte parameters and hemoglobin F production in sickle cell disease patients undergoing hydroxyurea therapy

Hemoglobin F (HbF) is an effective inhibitor of HbS polymerization. Hydroxyurea (HU) is used to increase HbF synthesis and improve the clinical course of sickle cell disease (SCD) patients. We studied a series of laboratory parameters concerning HbF production and reticulocyte response, and compared...

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Bibliografiske detaljer
Udgivet i:J Clin Lab Anal
Main Authors: Borba, R., Lima, C.S.P., Grotto, H.Z.W.
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Subscription Services, Inc., A Wiley Company 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807693/
https://ncbi.nlm.nih.gov/pubmed/12640630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.10070
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