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Curcumin stabilizes p53 by interaction with NAD(P)H:quinone oxidoreductase 1 in tumor-derived cell lines

Curcumin is a natural phytochemical with potent anti-neoplastic properties including modulation of p53. Targeting p53 activity has been suggested as an important strategy in cancer therapy. The purpose of this study was to describe a mechanism by which curcumin restores p53 levels in human cancer ce...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Patiño-Morales, Carlos César, Soto-Reyes, Ernesto, Arechaga-Ocampo, Elena, Ortiz-Sánchez, Elizabeth, Antonio-Véjar, Verónica, Pedraza-Chaverri, José, García-Carrancá, Alejandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807312/
https://ncbi.nlm.nih.gov/pubmed/31526948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101320
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