Disease Modification by Combinatorial Single Vector Gene Therapy: A Preclinical Translational Study in Epilepsy

Gene therapy has been suggested as a plausible novel approach to achieve seizure control in patients with focal epilepsy that do not adequately respond to pharmacological treatment. We investigated the seizure-suppressant potential of combinatorial neuropeptide Y and Y2 receptor single vector gene t...

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Bibliografiske detaljer
Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Melin, Esbjörn, Nanobashvili, Avtandil, Avdic, Una, Gøtzsche, Casper R., Andersson, My, Woldbye, David P.D., Kokaia, Merab
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807261/
https://ncbi.nlm.nih.gov/pubmed/31660420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.09.004
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