Development of Pyrosequencing Method for Detection of UGT1A1 Polymorphisms in Thai Colorectal Cancers

BACKGROUND: UGT1A1 is a polymorphic enzyme that has been associated with irinotecan drug metabolisms. We developed a pyrosequencing method to detect allele frequency and genotype of UGT1A1 polymorphisms (UGT1A1*28 and UGT1A1*6) in Thai colorectal cancer patients. METHOD: A pyrosequencing method was...

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Veröffentlicht in:J Clin Lab Anal
Hauptverfasser: Sukasem, Chonlaphat, Atasilp, Chalirmporn, Chansriwong, Pichai, Chamnanphon, Montri, Puangpetch, Apichaya, Sirachainan, Ekapob
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2014
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807135/
https://ncbi.nlm.nih.gov/pubmed/25545261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.21820
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