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MicroRNA Mediated Changes in Drug Metabolism and Target Gene Expression by Efavirenz and Rifampicin In Vitro: Clinical Implications

Efavirenz (EFV) and rifampicin (RMP) are widely prescribed in Africa for treatment of HIV/AIDS and tuberculosis epidemics. Exposure to medicines can alter drug metabolism, for example, through changes in expression of microRNAs. We report, in this study, novel observations on the ways in which EFV a...

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Detalhes bibliográficos
Publicado no:OMICS
Main Authors: Swart, Marelize, Dandara, Collet
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806364/
https://ncbi.nlm.nih.gov/pubmed/31526233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2019.0122
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