MicroRNA Mediated Changes in Drug Metabolism and Target Gene Expression by Efavirenz and Rifampicin In Vitro: Clinical Implications

Efavirenz (EFV) and rifampicin (RMP) are widely prescribed in Africa for treatment of HIV/AIDS and tuberculosis epidemics. Exposure to medicines can alter drug metabolism, for example, through changes in expression of microRNAs. We report, in this study, novel observations on the ways in which EFV a...

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Vydáno v:OMICS
Hlavní autoři: Swart, Marelize, Dandara, Collet
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806364/
https://ncbi.nlm.nih.gov/pubmed/31526233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2019.0122
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