MicroRNA Mediated Changes in Drug Metabolism and Target Gene Expression by Efavirenz and Rifampicin In Vitro: Clinical Implications

Efavirenz (EFV) and rifampicin (RMP) are widely prescribed in Africa for treatment of HIV/AIDS and tuberculosis epidemics. Exposure to medicines can alter drug metabolism, for example, through changes in expression of microRNAs. We report, in this study, novel observations on the ways in which EFV a...

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Publicat a:OMICS
Autors principals: Swart, Marelize, Dandara, Collet
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc., publishers 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806364/
https://ncbi.nlm.nih.gov/pubmed/31526233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2019.0122
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