Attenuation of Live-Attenuated Yellow Fever 17D Vaccine Virus Is Localized to a High-Fidelity Replication Complex

The molecular basis of attenuation for live-attenuated vaccines is poorly understood. The yellow fever (YF) 17D vaccine virus was derived from the wild-type, parental strain Asibi virus by serial passage in chicken tissue and has proven to be a very safe and efficacious vaccine. We have previously s...

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Опубликовано в: :mBio
Главные авторы: Davis, Emily H., Beck, Andrew S., Strother, Ashley E., Thompson, Jill K., Widen, Steven G., Higgs, Stephen, Wood, Thomas G., Barrett, Alan D. T.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805994/
https://ncbi.nlm.nih.gov/pubmed/31641088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02294-19
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