Sequence variants with large effects on cardiac electrophysiology and disease

Features of the QRS complex of the electrocardiogram, reflecting ventricular depolarisation, associate with various physiologic functions and several pathologic conditions. We test 32.5 million variants for association with ten measures of the QRS complex in 12 leads, using 405,732 electrocardiogram...

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Publicado no:Nat Commun
Main Authors: Norland, Kristjan, Sveinbjornsson, Gardar, Thorolfsdottir, Rosa B., Davidsson, Olafur B., Tragante, Vinicius, Rajamani, Sridharan, Helgadottir, Anna, Gretarsdottir, Solveig, van Setten, Jessica, Asselbergs, Folkert W., Sverrisson, Jon Th., Stephensen, Sigurdur S., Oskarsson, Gylfi, Sigurdsson, Emil L., Andersen, Karl, Danielsen, Ragnar, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Arnar, David O., Sulem, Patrick, Holm, Hilma, Gudbjartsson, Daniel F., Stefansson, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805929/
https://ncbi.nlm.nih.gov/pubmed/31641117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12682-9
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