Sequence variants with large effects on cardiac electrophysiology and disease

Features of the QRS complex of the electrocardiogram, reflecting ventricular depolarisation, associate with various physiologic functions and several pathologic conditions. We test 32.5 million variants for association with ten measures of the QRS complex in 12 leads, using 405,732 electrocardiogram...

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Publicat a:Nat Commun
Autors principals: Norland, Kristjan, Sveinbjornsson, Gardar, Thorolfsdottir, Rosa B., Davidsson, Olafur B., Tragante, Vinicius, Rajamani, Sridharan, Helgadottir, Anna, Gretarsdottir, Solveig, van Setten, Jessica, Asselbergs, Folkert W., Sverrisson, Jon Th., Stephensen, Sigurdur S., Oskarsson, Gylfi, Sigurdsson, Emil L., Andersen, Karl, Danielsen, Ragnar, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Arnar, David O., Sulem, Patrick, Holm, Hilma, Gudbjartsson, Daniel F., Stefansson, Kari
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805929/
https://ncbi.nlm.nih.gov/pubmed/31641117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12682-9
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