A missense variant in PLEC increases risk of atrial fibrillation

BACKGROUND: Genome-wide association studies (GWAS) have yielded variants at over 30 loci that associate with atrial fibrillation (AF), including rare coding mutations in the sarcomere genes MYH6 and MYL4. OBJECTIVES: The aim of this study was to search for novel AF associations and to gain insights...

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Publicat a:J Am Coll Cardiol
Autors principals: Thorolfsdottir, Rosa B., Sveinbjornsson, Gardar, Sulem, Patrick, Helgadottir, Anna, Gretarsdottir, Solveig, Benonisdottir, Stefania, Magnusdottir, Audur, Davidsson, Olafur B., Rajamani, Sridharan, Roden, Dan M., Darbar, Dawood, Pedersen, Terje R., Sabatine, Marc S., Jonsdottir, Ingileif, Arnar, David O., Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Holm, Hilma, Stefansson, Kari
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704994/
https://ncbi.nlm.nih.gov/pubmed/29050564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2017.09.005
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