The proposed systemic thermogenic metabolites succinate and 12,13-diHOME are inversely associated with adiposity and related metabolic traits: evidence from a large human cross-sectional study

AIMS/HYPOTHESIS: Circulating succinate and 12,13-dihydroxy-9Z-octadecenoic acid (12,13-diHOME) were recently shown to promote brown adipocyte thermogenesis and protect against metabolic disorders in rodents. This study aimed to evaluate the associations between plasma levels of these metabolites and...

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Udgivet i:Diabetologia
Main Authors: Vasan, Senthil K., Noordam, Raymond, Gowri, Mahasampath S., Neville, Matthew J., Karpe, Fredrik, Christodoulides, Constantinos
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805813/
https://ncbi.nlm.nih.gov/pubmed/31309263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-019-4947-5
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