Phenotypically distinct anti-insulin B cells repopulate pancreatic islets after anti-CD20 treatment in NOD mice

AIMS/HYPOTHESIS: Autoreactive B cells escape immune tolerance and contribute to the pathogenesis of type 1 diabetes. While global B cell depletion is a successful therapy for autoimmune disease, the fate of autoreactive cells during this treatment in autoimmune diabetes is unknown. We aimed to ident...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Diabetologia
Hlavní autoři: Boldison, Joanne, Da Rosa, Larissa C., Buckingham, Lucy, Davies, Joanne, Wen, Li, Wong, F. Susan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805803/
https://ncbi.nlm.nih.gov/pubmed/31444529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-019-04974-y
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky