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Notch pathway: a bistable inducer of biological noise?

ABSTRACT: Notch signalling pathway is central to development of metazoans. The pathway codes a binary fate switch. Upon activation, downstream signals contribute to resolution of fate dichotomies such as proliferation/differentiation or sub-lineage differentiation outcome. There is, however, an inte...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Vujovic, Filip, Hunter, Neil, Farahani, Ramin M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805690/
https://ncbi.nlm.nih.gov/pubmed/31640734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0453-0
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