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Genomic competition for noise reduction shaped evolutionary landscape of mir-4673

The genomic platform that informs evolution of microRNA cascades remains unknown. Here we capitalised on the recent evolutionary trajectory of hominin-specific miRNA-4673, encoded in intron 4 of notch-1, to uncover the identity of one such precursor genomic element and the selective forces acting up...

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Detalhes bibliográficos
Publicado no:NPJ Syst Biol Appl
Main Authors: Farahani, Ramin M., Rezaei-Lotfi, Saba, Hunter, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203229/
https://ncbi.nlm.nih.gov/pubmed/32376854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-020-0131-2
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