Targeting tauopathy with engineered tau-degrading intrabodies

BACKGROUND: The accumulation of pathological tau is the main component of neurofibrillary tangles and other tau aggregates in several neurodegenerative diseases, referred to as tauopathies. Recently, immunotherapeutic approaches targeting tau have been demonstrated to be beneficial in decreasing tau...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mol Neurodegener
Hlavní autoři: Gallardo, Gilbert, Wong, Connie H., Ricardez, Sara M., Mann, Carolyn N., Lin, Kent H., Leyns, Cheryl E. G., Jiang, Hong, Holtzman, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805661/
https://ncbi.nlm.nih.gov/pubmed/31640765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0340-6
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky