Targeting tauopathy with engineered tau-degrading intrabodies

BACKGROUND: The accumulation of pathological tau is the main component of neurofibrillary tangles and other tau aggregates in several neurodegenerative diseases, referred to as tauopathies. Recently, immunotherapeutic approaches targeting tau have been demonstrated to be beneficial in decreasing tau...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Neurodegener
Päätekijät: Gallardo, Gilbert, Wong, Connie H., Ricardez, Sara M., Mann, Carolyn N., Lin, Kent H., Leyns, Cheryl E. G., Jiang, Hong, Holtzman, David M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2019
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805661/
https://ncbi.nlm.nih.gov/pubmed/31640765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0340-6
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