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Targeting tauopathy with engineered tau-degrading intrabodies
BACKGROUND: The accumulation of pathological tau is the main component of neurofibrillary tangles and other tau aggregates in several neurodegenerative diseases, referred to as tauopathies. Recently, immunotherapeutic approaches targeting tau have been demonstrated to be beneficial in decreasing tau...
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| Published in: | Mol Neurodegener |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6805661/ https://ncbi.nlm.nih.gov/pubmed/31640765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0340-6 |
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