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Rupintrivir reduces RV-induced T(H)-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo

BACKGROUND: Antiviral drugs such as rupintrivir may have an immune-modulatory effect in experimentally induced allergic asthma with subsequent RV infection. We infected lung slices of house-dust mite (HDM)-sensitized asthmatic mice ex vivo with human rhinovirus (RV) and investigated the effect of th...

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Bibliografische gegevens
Gepubliceerd in:Respir Res
Hoofdauteurs: Danov, Olga, Lasswitz, Lisa, Obernolte, Helena, Hesse, Christina, Braun, Armin, Wronski, Sabine, Sewald, Katherina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805592/
https://ncbi.nlm.nih.gov/pubmed/31640701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1175-y
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