Rupintrivir reduces RV-induced T(H)-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo

BACKGROUND: Antiviral drugs such as rupintrivir may have an immune-modulatory effect in experimentally induced allergic asthma with subsequent RV infection. We infected lung slices of house-dust mite (HDM)-sensitized asthmatic mice ex vivo with human rhinovirus (RV) and investigated the effect of th...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Danov, Olga, Lasswitz, Lisa, Obernolte, Helena, Hesse, Christina, Braun, Armin, Wronski, Sabine, Sewald, Katherina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805592/
https://ncbi.nlm.nih.gov/pubmed/31640701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1175-y
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