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Discovery of low-molecular weight anti-PD-L1 peptides for cancer immunotherapy

BACKGROUND: Immunotherapy using checkpoint inhibitors, especially PD-1/PD-L1 inhibitors, has now evolved into the most promising therapy for cancer patients. However, most of these inhibitors are monoclonal antibodies, and their large size may limit their tumor penetration, leading to suboptimal eff...

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Dettagli Bibliografici
Pubblicato in:J Immunother Cancer
Autori principali: Liu, Hao, Zhao, Zhen, Zhang, Li, Li, Yuanke, Jain, Akshay, Barve, Ashutosh, Jin, Wei, Liu, Yanli, Fetse, John, Cheng, Kun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805442/
https://ncbi.nlm.nih.gov/pubmed/31640814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0705-y
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