Metformin overcomes resistance to cisplatin in triple-negative breast cancer (TNBC) cells by targeting RAD51

BACKGROUND: Chemotherapy is a standard therapeutic regimen to treat triple-negative breast cancer (TNBC); however, chemotherapy alone does not result in significant improvement and often leads to drug resistance in patients. In contrast, combination therapy has proven to be an effective strategy for...

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Veröffentlicht in:Breast Cancer Res
Hauptverfasser: Lee, Jung Ok, Kang, Min Ju, Byun, Won Seok, Kim, Shin Ae, Seo, Il Hyeok, Han, Jeong Ah., Moon, Ji Wook, Kim, Ji Hae, Kim, Su Jin, Lee, Eun Jung, In Park, Serk, Park, Sun Hwa, Kim, Hyeon Soo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805313/
https://ncbi.nlm.nih.gov/pubmed/31640742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1204-2
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