Identification of a systemic interferon-γ inducible antimicrobial gene signature in leprosy patients undergoing reversal reaction

Reversal reactions (RRs) in leprosy are characterized by a reduction in the number of bacilli in lesions associated with an increase in cell-mediated immunity against the intracellular bacterium Mycobacterium leprae, the causative pathogen of leprosy. To identify the mechanisms that contribute to ce...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: Teles, Rosane M. B., Lu, Jing, Tió-Coma, Maria, Goulart, Isabela M. B., Banu, Sayera, Hagge, Deanna, Bobosha, Kidist, Ottenhoff, Tom H. M., Pellegrini, Matteo, Geluk, Annemieke, Modlin, Robert L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805014/
https://ncbi.nlm.nih.gov/pubmed/31600201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007764
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