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Lower Insulin Clearance Parallels a Reduced Insulin Sensitivity in Obese Youths and Is Associated With a Decline in β-Cell Function Over Time

We examined the relationship between insulin clearance, insulin sensitivity, and β-cell function and the longitudinal effect of insulin clearance on β-cell function in lean and obese insulin-sensitive and insulin-resistant adolescents. A hyperinsulinemic-euglycemic and a hyperglycemic clamp were per...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Galderisi, Alfonso, Polidori, David, Weiss, Ram, Giannini, Cosimo, Pierpont, Bridget, Tricò, Domenico, Caprio, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804624/
https://ncbi.nlm.nih.gov/pubmed/31399433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0120
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