Evidence for Early Defects in Insulin Sensitivity and Secretion Before the Onset of Glucose Dysregulation in Obese Youths : A Longitudinal Study

We sought to determine whether obese adolescents with high-“normal” 2-h post-oral glucose tolerance test glucose levels display defects in insulin secretion and sensitivity associated with future development of impaired glucose tolerance (IGT). Insulin sensitivity was measured by hyperinsulinemic-eu...

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Autors principals: Giannini, Cosimo, Weiss, Ram, Cali, Anna, Bonadonna, Riccardo, Santoro, Nicola, Pierpont, Bridget, Shaw, Melissa, Caprio, Sonia
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2012
Matèries:
Obesity Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282810/
https://ncbi.nlm.nih.gov/pubmed/22315322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1111
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