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Constrained Mutational Sampling of Amino Acids in HIV-1 Protease Evolution

The evolution of HIV-1 protein sequences should be governed by a combination of factors including nucleotide mutational probabilities, the genetic code, and fitness. The impact of these factors on protein sequence evolution is interdependent, making it challenging to infer the individual contributio...

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Dades bibliogràfiques
Publicat a:Mol Biol Evol
Autors principals: Boucher, Jeffrey I, Whitfield, Troy W, Dauphin, Ann, Nachum, Gily, Hollins, Carl, Zeldovich, Konstantin B, Swanstrom, Ronald, Schiffer, Celia A, Luban, Jeremy, Bolon, Daniel N A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804413/
https://ncbi.nlm.nih.gov/pubmed/30721995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz022
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