Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats

In angiotensin II (Ang II)-dependent hypertensive rats there is an increased expression of proximal tubule angiotensinogen (AGT), collecting duct renin and angiotensin converting enzyme (ACE), which contributes to intratubular Ang II formation. Ang II acts on Ang II type 1 receptors promoting sodium...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Gonzalez, Alexis A., Gallardo, Matias, Cespedes, Carlos, Vio, Carlos P.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804396/
https://ncbi.nlm.nih.gov/pubmed/31680980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01212
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