Impaired development of a miltefosine-resistant Leishmania infantum strain in the sand fly vectors Phlebotomus perniciosus and Lutzomyia longipalpis

OBJECTIVES: To gain insight into the propagation of miltefosine (MIL) resistance in visceral leishmaniasis, this laboratory study explored development of resistant parasites with a defective miltefosine transporter (MT) in sand flies. METHODS: Infectivity, colonization of stomodeal valve and metacyc...

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Udgivet i:Int J Parasitol Drugs Drug Resist
Main Authors: Van Bockstal, Lieselotte, Sádlová, Jovana, Suau, Hamide Aslan, Hendrickx, Sarah, Meneses, Claudio, Kamhawi, Shaden, Volf, Petr, Maes, Louis, Caljon, Guy
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804374/
https://ncbi.nlm.nih.gov/pubmed/31525614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2019.09.003
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