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Differential Mechanism of ATP Production Occurs in Response to Succinylacetone in Colon Cancer Cells

Our aim was to verify the potential ability of succinylacetone (SA) to inhibit mitochondrial function, thereby suppressing cancer cell proliferation. SA treatment caused apoptosis in HCT116 and HT29 cells, but not in SW480 cells, with mitochondria playing a key role. We checked for dysfunctional mit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Lee, Phil Jun, Woo, Seung Je, Yoo, Hee Min, Cho, Namki, Kim, Hong Pyo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803967/
https://ncbi.nlm.nih.gov/pubmed/31623369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24193575
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