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Differential Mechanism of ATP Production Occurs in Response to Succinylacetone in Colon Cancer Cells

Our aim was to verify the potential ability of succinylacetone (SA) to inhibit mitochondrial function, thereby suppressing cancer cell proliferation. SA treatment caused apoptosis in HCT116 and HT29 cells, but not in SW480 cells, with mitochondria playing a key role. We checked for dysfunctional mit...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lee, Phil Jun, Woo, Seung Je, Yoo, Hee Min, Cho, Namki, Kim, Hong Pyo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803967/
https://ncbi.nlm.nih.gov/pubmed/31623369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24193575
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