Computer-Aided Discovery of Small Molecule Inhibitors of Thymocyte Selection-Associated High Mobility Group Box Protein (TOX) as Potential Therapeutics for Cutaneous T-Cell Lymphomas

Cutaneous T-cell lymphomas (CTCL) are the most common primary lymphomas of the skin. We have previously identified thymocyte selection-associated high mobility group (HMG) box protein (TOX) as a promising drug target in CTCL; however, there are currently no small molecules able to directly inhibit T...

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Vydáno v:Molecules
Hlavní autoři: Agrawal, Vibudh, Su, Mingwan, Huang, Yuanshen, Hsing, Michael, Cherkasov, Artem, Zhou, Youwen
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803922/
https://ncbi.nlm.nih.gov/pubmed/31554191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24193459
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