Atroxlysin-III, A Metalloproteinase from the Venom of the Peruvian Pit Viper Snake Bothrops atrox (Jergón) Induces Glycoprotein VI Shedding and Impairs Platelet Function

Atroxlysin-III (Atr-III) was purified from the venom of Bothrops atrox. This 56-kDa protein bears N-linked glycoconjugates and is a P-III hemorrhagic metalloproteinase. Its cDNA-deduced amino acid sequence reveals a multidomain structure including a proprotein, a metalloproteinase, a disintegrin-lik...

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Vydáno v:Molecules
Hlavní autoři: Oliveira, Luciana S., Estevão-Costa, Maria Inácia, Alvarenga, Valéria G., Vivas-Ruiz, Dan E., Yarleque, Armando, Lima, Augusto Martins, Cavaco, Ana, Eble, Johannes A., Sanchez, Eladio F.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803841/
https://ncbi.nlm.nih.gov/pubmed/31561469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24193489
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