Randomized Phase II Trial of Triapine-Cisplatin-Radiotherapy for Locally Advanced Stage Uterine Cervix or Vaginal Cancers

Uterine cervix or vaginal cancers have inherent overactivity of ribonucleotide reductase (RNR), making these cancers rational targets for therapy based on interruption of cisplatin-radiotherapy-induced DNA damage repair. We conducted a pilot, open-label randomized phase II trial to evaluate the effi...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Kunos, Charles A., Andrews, Stephen J., Moore, Kathleen N., Chon, Hye Sook, Ivy, S. Percy
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803528/
https://ncbi.nlm.nih.gov/pubmed/31681600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01067
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