Intradermal or Sublingual Delivery and Heat-Labile Enterotoxin Proteins Shape Immunologic Responses to a CFA/I Fimbria-Derived Subunit Antigen Vaccine against Enterotoxigenic Escherichia coli

Enterotoxigenic Escherichia coli (ETEC) is a major cause of infectious diarrhea in children, travelers, and deployed military personnel. As such, development of a vaccine would be advantageous for public health. One strategy is to use subunits of colonization factors combined with antigen/adjuvant t...

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Udgivet i:Infect Immun
Main Authors: Maciel, Milton, Bauer, David, Baudier, Robin L., Bitoun, Jacob, Clements, John D., Poole, Steven T., Smith, Mark A., Kaminski, Robert W., Savarino, Stephen J., Norton, Elizabeth B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803349/
https://ncbi.nlm.nih.gov/pubmed/31427449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00460-19
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