Long Noncoding RNA Lnc-MxA Inhibits Beta Interferon Transcription by Forming RNA-DNA Triplexes at Its Promoter

Previously, we identified a set of long noncoding RNAs (lncRNAs) that were differentially expressed in influenza A virus (IAV)-infected cells. In this study, we focused on lnc-MxA, which is upregulated during IAV infection. We found that the overexpression of lnc-MxA facilitates the replication of I...

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Veröffentlicht in:J Virol
Hauptverfasser: Li, Xinda, Guo, Guijie, Lu, Min, Chai, Wenjia, Li, Yucen, Tong, Xiaomei, Li, Jing, Jia, Xiaojuan, Liu, Wenjun, Qi, Dandan, Ye, Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803265/
https://ncbi.nlm.nih.gov/pubmed/31434735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00786-19
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