Interferon-induced Antiviral Protein MxA Interacts with the Cellular RNA Helicases UAP56 and URH49

Mx proteins are a family of large GTPases that are induced exclusively by interferon-α/β and have a broad antiviral activity against several viruses, including influenza A virus (IAV). Although the antiviral activities of mouse Mx1 and human MxA have been studied extensively, the molecular mechanism...

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Main Authors: Wisskirchen, Christian, Ludersdorfer, Thomas H., Müller, Dominik A., Moritz, Eva, Pavlovic, Jovan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186362/
https://ncbi.nlm.nih.gov/pubmed/21859714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251843
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