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The HIV-1 Antisense Protein ASP Is a Transmembrane Protein of the Cell Surface and an Integral Protein of the Viral Envelope

The negative strand of HIV-1 encodes a highly hydrophobic antisense protein (ASP) with no known homologs. The presence of humoral and cellular immune responses to ASP in HIV-1 patients indicates that ASP is expressed in vivo, but its role in HIV-1 replication remains unknown. We investigated ASP exp...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Affram, Yvonne, Zapata, Juan C., Gholizadeh, Zahra, Tolbert, William D., Zhou, Wei, Iglesias-Ussel, Maria D., Pazgier, Marzena, Ray, Krishanu, Latinovic, Olga S., Romerio, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803264/
https://ncbi.nlm.nih.gov/pubmed/31434734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00574-19
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