Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk

Autophagy is a homeostatic cellular process involved in the degradation of long-lived or damaged cellular components. The role of autophagy in adipogenesis is well recognized, but its role in mature adipocyte function is largely unknown. We show that the autophagy proteins Atg3 and Atg16L1 are requi...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Cai, Jinjin, Pires, Karla M., Ferhat, Maroua, Chaurasia, Bhagirath, Buffolo, Ma´rcio A., Smalling, Rana, Sargsyan, Ashot, Atkinson, Donald L., Summers, Scott A., Graham, Timothy E., Boudina, Sihem
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802939/
https://ncbi.nlm.nih.gov/pubmed/30428342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.040
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