Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis

Obesity and insulin resistance are associated with oxidative stress (OS). The causal role of adipose OS in the pathogenesis of these conditions is unknown. To address this issue, we generated mice with an adipocyte-selective deletion of manganese superoxide dismutase (MnSOD). When fed a high-fat die...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Diabetes
Main Authors: Han, Yong Hwan, Buffolo, Márcio, Pires, Karla Maria, Pei, Shaobo, Scherer, Philipp E., Boudina, Sihem
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2016
Teme:
Obesity Studies
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001177/
https://ncbi.nlm.nih.gov/pubmed/27284109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0283
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki