The Synaptic Targeting of mGluR1 by Its Carboxyl-Terminal Domain Is Crucial for Cerebellar Function

The metabotropic glutamate receptor subtype 1 (mGluR1, Grm1) in cerebellar Purkinje cells (PCs) is essential for motor coordination and motor learning. At the synaptic level, mGluR1 has a critical role in long-term synaptic depression (LTD) at parallel fiber (PF)-PC synapses, and in developmental el...

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Vydáno v:J Neurosci
Hlavní autoři: Ohtani, Yoshiaki, Miyata, Mariko, Hashimoto, Kouichi, Tabata, Toshihide, Kishimoto, Yasushi, Fukaya, Masahiro, Kase, Daisuke, Kassai, Hidetoshi, Nakao, Kazuki, Hirata, Tatsumi, Watanabe, Masahiko, Kano, Masanobu, Aiba, Atsu
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802745/
https://ncbi.nlm.nih.gov/pubmed/24523559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3542-13.2014
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