Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats

Microbial metabolites have emerged as critical components that mediate the metabolic effects of the gut microbiota. Here, we show that indole-3-propionic acid (IPA), a tryptophan metabolite produced by gut bacteria, is a potent anti-non-alcoholic steatohepatitis (NASH) microbial metabolite. Here, we...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Zhao, Ze-Hua, Xin, Feng-Zhi, Xue, Yaqian, Hu, Zhimin, Han, Yamei, Ma, Fengguang, Zhou, Da, Liu, Xiao-Lin, Cui, Aoyuan, Liu, Zhengshuai, Liu, Yuxiao, Gao, Jing, Pan, Qin, Li, Yu, Fan, Jian-Gao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802644/
https://ncbi.nlm.nih.gov/pubmed/31506421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0304-5
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