Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats

Microbial metabolites have emerged as critical components that mediate the metabolic effects of the gut microbiota. Here, we show that indole-3-propionic acid (IPA), a tryptophan metabolite produced by gut bacteria, is a potent anti-non-alcoholic steatohepatitis (NASH) microbial metabolite. Here, we...

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Dades bibliogràfiques
Publicat a:Exp Mol Med
Autors principals: Zhao, Ze-Hua, Xin, Feng-Zhi, Xue, Yaqian, Hu, Zhimin, Han, Yamei, Ma, Fengguang, Zhou, Da, Liu, Xiao-Lin, Cui, Aoyuan, Liu, Zhengshuai, Liu, Yuxiao, Gao, Jing, Pan, Qin, Li, Yu, Fan, Jian-Gao
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802644/
https://ncbi.nlm.nih.gov/pubmed/31506421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0304-5
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