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Feature article: δ-Aminolevulinate induces fetal hemoglobin expression by enhancing cellular heme biosynthesis

Sickle cell disease (SCD) and β-thalassemia are inherited blood disorders caused by genetic defects in the β-globin gene on chromosome 11, producing severe disease in people worldwide. Induction of fetal hemoglobin consisting of two α-globin and two γ-globin chains ameliorates the clinical symptoms...

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Bibliografske podrobnosti
izdano v:Exp Biol Med (Maywood)
Main Authors: Liu, Li, Zhu, Xingguo, Yu, Alexander, Ward, Christina M, Pace, Betty S
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802153/
https://ncbi.nlm.nih.gov/pubmed/31475864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219872995
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